Eosinophilic fasciitis

A syndrome characterized by tenderness and swelling of the extremities caused by inflammation of the fascia and muscles.

Causes, incidence, and risk factors

The cause of eosinophilic fasciitis is unknown. There is an infiltration of eosinophils , a type of white blood cell, into the affected fascia and muscles. Eosinophils are associated with allergic-type reactions, but their specific function is largely unknown. The arms, legs, trunk, and face may be affected by joint contractures , muscle weakness , and changes in the overlying skin. The syndrome in some cases appears to be precipitated by strenuous physical activity . Any age may be affected, but most people are between 30 and 60 years old.

Signs and tests

  • erythrocyte sedimentation rate
  • , elevated
  • hypergammaglobulinemia
  • muscle biopsy
  • , including fascia tissue
  • skin biopsy
  • , including fascia tissue
  • Treatment

    Treatment with corticosteroid medications provides relief of the symptoms, especially when it is started early in the disease course.

    Expectations (prognosis)

    Most people have a resolution of this illness within 3 to 5 years. Some recurrences of the illness or persistent disease have been noted.

    Complications

  • arthritis
  • (rare)
  • Calling your health care provider

    Call for an appointment with your health care provider if symptoms of this disorder develop.

    Prevention

    There is no known prevention, because the cause is unknown.

    Treatment Options – Sorted by Soonest Available

    URGENT CARE

    Save up to versus Emergency Room Visit

    Find Nearest Urgent Care

    Please enter Zip Code for nearest facility

    Cost:
    |
    Av. Wait Time: 3 Min.

    EMERGENCY ROOM

    Find Nearest ER

    Please enter Zip Code for nearest facility

    Cost:
    |
    Av. Wait Time: 1 - 8 Hrs.

    PRIMARY CARE

    Find Nearest Primary Care

    Please enter Zip Code for nearest facility

    Cost:
    |
    Av. Wait Time: 1 - 10 Days

    News related to "Eosinophilic fasciitis"